A naturally occurring human antimicrobial peptide — your body already makes it. Supplementation supports innate immune defense against bacterial, viral, and fungal pathogens.
LL-37 is the only cathelicidin antimicrobial peptide found in humans. It disrupts microbial cell membranes, modulates innate immune responses, promotes wound healing, and has anti-biofilm properties. It bridges innate and adaptive immunity by recruiting immune cells to infection sites and modulating inflammatory responses.
Women face unique infection risks throughout life — urinary tract infections, vaginal infections, and post-surgical infections are all areas where antimicrobial peptide support may be relevant. LL-37 production can decline with vitamin D deficiency (common in women) and aging, potentially contributing to increased infection susceptibility.
As a Category 2 peptide, LL-37 has limited human safety data from controlled trials. Its status as a naturally occurring human peptide suggests baseline tolerability, but therapeutic dosing data is limited. Injection site reactions are possible.
LL-37 is a naturally occurring human peptide, which is generally a positive safety signal. However, it is classified as Category 2 by the FDA, meaning limited human safety data from controlled trials. Discuss with your provider.
The FDA classified LL-37 as Category 2 due to limited human clinical safety data, not due to demonstrated safety concerns. This means it faces additional regulatory scrutiny for compounding.
Part of our Gut & Immune Health hub.
Medical Disclaimer: This profile is for educational purposes only. Always consult a licensed healthcare provider before starting any peptide therapy.
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